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Warfarin pharmacogenetics.
N Engl J Med. 2009 Jun 4;360(23):2474; author reply 2475
Authors: Garcia DA, Hylek E
PMID: 19494226 [PubMed - indexed for MEDLINE]
The pharmacogenetics and pharmacodynamics of clopidogrel response: an analysis from the PRINC (Plavix Response in Coronary Intervention) trial.
JACC Cardiovasc Interv. 2008 Dec;1(6):620-7
Authors: Gladding P, Webster M, Zeng I, Farrell H, Stewart J, Ruygrok P, Ormiston J, El-Jack S, Armstrong G, Kay P, Scott D, Gunes A, Dahl ML
OBJECTIVES: This study assessed the effect of pharmacogenetics on the antiplatelet effect of clopidogrel.
Personalized Medicine: Challenges Slow Progress
Researchers Detail Challenges of Personalized Medicine in Colloquium at AAAS
Despite much hope—and hype—on progress toward cutting-edge tailored therapies, researchers said at AAAS that personalized medicine is proving more complex than expected.
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FDA Partners with GlaxoSmithKline and Adaptive Pharmacogenomics to Advance Personalized Medicine
JNCI news brief: Improving the biomarker pipeline for early cancer detection
E-health Enables More Personalized Medicine; Group Fights For Digital Patient Rights
Promising biomarker and candidate tumor suppressor gene identified for colorectal cancer
Polymorphism of human cytochrome P450 enzymes and its clinical impact.
Drug Metab Rev. 2009;41(2):89-295
Authors: Zhou SF, Liu JP, Chowbay B
Pharmacogenetics is the study of how interindividual variations in the DNA sequence of specific genes affect drug response.
Glucocorticoid replacement therapy and pharmacogenetics in Addison's disease: effects on bone.
Eur J Endocrinol. 2009 Jun;160(6):993-1002
Authors: Løvås K, Gjesdal CG, Christensen M, Wolff AB, Almås B, Svartberg J, Fougner KJ, Syversen U, Bollerslev J, Falch JA, Hunt PJ, Chatterjee VK, Husebye ES
Context Patients with primary adrenal insufficiency (Addison's disease) receive more glucococorticoids than the normal endogenous production, raising concern about adverse effects on bone.